[find our papers on PubMed]
* co-first author; ¶ co-corresponding author

2018 (2)

Germline Lysine-Specific Demethylase 1 (LSD1/KDM1A) Mutations Confer Susceptibility to Multiple Myeloma
Wei X, Calvo-Vidal N, Chen S, Wu G, Revuelta M, Sun J, Zhang J, Walsh M, Nichols K, Joseph V, Snyder C, Vachon C, McKay J, Wang S, Jayabalan D, Jacobs L, Becirovic D, Waller R, Artomov M, Viale A, Patel J, Phillip J, Chen-Kiang S, Curtin K, Salama M, Atanackovic D, Niesvizky R, Landgren O, Slager S, Godley L, Churpek J, Garber J, Anderson K, Daly M, Roeder R, Dumontet C, Lynch H, Mullighan C, Camp N, Offit K, Klein R¶, Yu H¶, Cerchietti L¶, and Lipkin S¶. Cancer Research 2018 March 20.
Interactome INSIDER: a structural interactome browser for genomic studies
Meyer M, Beltrán J, Liang S, Fragoza R, Rumack A, Liang J, Wei X, and Yu H. Nature Methods 2018 January 1 doi:10.1038/nmeth.4540.

2017 (1)

GeMSTONE: orchestrated prioritization of human germline mutations in the cloud
Chen S, Beltrán J, Esteban-Jurado C, Franch-Expósito S, Castellví-Bel S, Lipkin S, Wei X, and Yu H. Nucleic Acids Res 2017 May 18.

2016 (1)

A Proteome-wide Fission Yeast Interactome Reveals Network Evolution Principles from Yeasts to Human
Vo TV, Das J, Meyer MJ, Cordero NA, Akturk N, Wei X, Fair BJ, Degatano AG, Fragoza R, Liu LG, Matsuyama A, Trickey M, Horibata S, Grimson A, Yamano H, Yoshida M, Roth FP, Pleiss JA, Xia Y, Yu H. Cell 2016 Jan 14 164(1): 310 - 323.

2014 (2)

A Massively Parallel Pipeline to Clone DNA Variants and Examine Molecular Phenotypes of Human Disease Mutations
Wei X, Das J, Fragoza R, Liang J, Bastos de Oliviera FM, Lee HR, Wang X, Mort M, Stenson PD, Cooper DN, Lipkin SM, Smolka MB, Yu H. PLoS Genetics 2014 Dec 11 10(12): e1004819.
Elucidating common structural features of human pathogenic variations using large-scale atomic-resolution protein networks
Das J, Lee HR, Sagar A, Fragoza R, Liang J, Wei X, Wang X, Mort M, Stenson PD, Cooper DN and Yu H. Human Mutation 2014 May 35(5):585-593.
Featured as a video highlight in Human Mutation

2013 (3)

Integrative annotation of variants from 1,092 humans: application to cancer genomics
Khurana E, Fu Y, Colonna V, Mu XJ, Kang HM, Lappalainen T, Sboner A, Lochovsky L, Chen J, Harmanci A, Das J, Abyzov A, Balasubramanian S, Beal K, Chakravarty D, Challis D, Chen Y, Clarke D, Clarke L, Cunningham F, Evani US, Flicek P, Fragoza R, Garrison E, Gibbs R, Gümüş ZH, Herrero J, Kitabayashi N, Kong Y, Lage K, Liluashvili V, Lipkin S, MacArthur DG, Marth G, Muzny D, Pers TH, Ritchi G, Rosenfeld JA, Sisu C, Wei X, Wilson M, Xue Y, Yu F, 1000 Genomes Project Consortium, Dermitzakis ET, Yu H, Rubin MA, Tyler-Smith C, Gerstein M. Science 2013 Oct 342 (6154), 1235587.
Highlighted as "Research Highlights" in Nature, 2013, 502: 144
Dissecting disease inheritance modes in a 3D protein network challenges the "guilt-by-association" principle
Guo Y, Wei X, Das J, Grimson A, Lipkin SM, Clark AG and Yu H. Am J Hum Genet 2013 July 11 3(1):78-89.
Highlighted in "This Month in The Journal" in Am J Hum Genet 2013, 3(1):1-2, and in "This Month in the American Journal of Human Genetics" in Genetics 2013, 197(3)
Cross-species protein interactome mapping reveals species-specific wiring of stress-response pathways
Das J, Vo T, Wei X, Mellor JC, Tong V, Degatano AG, Wang X, Wang L, Cordero NA, Kruer-Zerhusen N, Matsuyama A, Pleiss JA, Lipkin SM, Yoshida M, Roth FP and Yu H. Science Signaling 2013 6, ra38.
Evaluated as "Very Good" by "FACULTY of 1000".

2012 (1)

Three-dimensional reconstruction of protein networks provides insight into human genetic disease
Wang X, Wei X, Thijssen B, Das J, Lipkin SM, and Yu H. Nature Biotechnology 2012 Jan 15 30(2):159-64.
Highlighted as "Research Highlights" in Nature Methods, 2012, 9: 220-1, as "Technology Feature" in Nature, 2012, 484: 271-5, and as "Feature" and on the cover of Nature, 2013, 494:416-9; Evaluated as "Exceptional" by "FACULTY of 1000."